Epitope imprinted polymeric materials: application in electrochemical detection of disease biomarkers
Ayushi Singhal, Amrita Singh, Apoorva Shrivastava, Raju Khan
Abstract
, traditional molecular imprinting techniques with regards to the large size of proteins, such as the size, complexity, accessibility, and conformational flexibility of the template. Electrochemical based sensors are proven to be promising tool for the quick, real-time monitoring of biomarkers. This review unravels epitope imprinting techniques, approaches, and strategies and highlights the applicability of these techniques for the electrochemical quantification of biomarkers for timely disease monitoring. In addition, some challenges are discussed along with future prospective developments.
Topics & Concepts
EpitopeMolecular imprintingNanotechnologyBioanalysisImprinting (psychology)Molecularly imprinted polymerFlexibility (engineering)TemplateComputer scienceComputational biologyMaterials scienceBiochemical engineeringBiologyAntigenSelectivityGeneEngineeringMathematicsBiochemistryStatisticsGeneticsCatalysisAnalytical chemistry methods developmentAdvanced biosensing and bioanalysis techniquesMicrofluidic and Capillary Electrophoresis Applications