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Design, synthesis and biological evaluation of novel 5,6,7-trimethoxy-N-aryl-2-styrylquinolin-4-amines as potential anticancer agents and tubulin polymerization inhibitors

Salimeh Mirzaei, Farhad Eisvand, Farzin Hadizadeh, Fatemeh Mosaffa, Ali Ghasemi, Razieh Ghodsi

2020Bioorganic Chemistry109 citationsDOI

Topics & Concepts

ChemistryCancer cellCytotoxic T cellTubulinAnnexinIn vitroCytotoxicityApoptosisCisplatinCell cultureOvarian cancerCancerCancer researchBiochemistryMicrotubuleBiologyCell biologyChemotherapyGeneticsSynthesis and biological activitySynthesis and Biological EvaluationMulticomponent Synthesis of Heterocycles
Design, synthesis and biological evaluation of novel 5,6,7-trimethoxy-N-aryl-2-styrylquinolin-4-amines as potential anticancer agents and tubulin polymerization inhibitors | Litcius