Phytochemical Screening, Quantification, FT-IR Analysis, and <i>In Silico</i> Characterization of Potential Bio-active Compounds Identified in HR-LC/MS Analysis of the Polyherbal Formulation from Northeast India
Prince Kumar Singh, Jagreeti Singh, Tapas Medhi, Aditya Kumar
Abstract
SwissADME analysis of identified compounds revealed 25 potential compounds following Lipinski's rule and showing drug-like characteristics, and out of them, 16 compounds exhibited good oral bioavailability, as revealed in the bioavailability radar. The overall study showed that the presented polyherbal formulation is enriched with bio-active phytochemical compounds with good pharmaceutical values.
Topics & Concepts
PhytochemicalBioavailabilityChemistryPhenolsAnthraquinonesTraditional medicineChromatographyPharmacologyBiochemistryMedicineBiologyBotanyNatural Antidiabetic Agents StudiesPhytochemicals and Antioxidant ActivitiesComputational Drug Discovery Methods