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MFN2-driven mitochondria-to-nucleus tethering allows a non-canonical nuclear entry pathway of the mitochondrial pyruvate dehydrogenase complex

Sotirios Zervopoulos, Aristeidis E. Boukouris, Bruno Saleme, Alois Haromy, Saymon Tejay, Gopinath Sutendra, Evangelos D. Michelakis

2022Molecular Cell68 citationsDOI

Topics & Concepts

BiologyCell biologyMFN2LaminInner membraneMitochondrionNuclear laminaCell nucleusmitochondrial fusionNucleusMitochondrial DNABiochemistryNuclear proteinTranscription factorGeneMitochondrial Function and PathologyNuclear Structure and FunctionATP Synthase and ATPases Research
MFN2-driven mitochondria-to-nucleus tethering allows a non-canonical nuclear entry pathway of the mitochondrial pyruvate dehydrogenase complex | Litcius