Mechanistic evaluation of the initial burst release of leuprolide from spray-dried PLGA microspheres
Richard Schutzman, Nianqiu Shi, Karl Olsen, Rose Ackermann, Jie Tang, Yayuan Liu, Justin K. Y. Hong, Yan Wang, Bin Qin, Anna Schwendeman, Steven P. Schwendeman
Topics & Concepts
PLGAMicroparticleControlled releaseSpray dryingDosage formChromatographyKineticsBioequivalenceChemistryPolymerParticle sizeMaterials scienceChemical engineeringBiomedical engineeringPharmacokineticsNanotechnologyNanoparticlePharmacologyMedicineOrganic chemistryEngineeringPhysical chemistryPhysicsQuantum mechanicsAdvanced Drug Delivery SystemsInhalation and Respiratory Drug DeliveryDrug Solubulity and Delivery Systems