C3 and ACE1 polymorphisms are more important confounders in the spread and outcome of COVID-19 in comparison with ABO polymorphism
Joris Delanghe, Marc De Buyzere, Marijn M. Speeckaert
Abstract
With interest, we read the paper of Dai, 1 regarding the association between ABO blood group and coronavirus disease-19 (COVID-19). The paper suggests that subjects with blood group A, especially those with cardiovascular diseases, in particular hypertension, need to be quarantined and protected from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or need to be under special medical care to be prevented from deterioration and severe progression.
Topics & Concepts
MedicineCoronavirus disease 2019 (COVID-19)ConfoundingABO blood group system2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Polymorphism (computer science)Internal medicineGenotypeVirologyGeneticsInfectious disease (medical specialty)DiseaseOutbreakGeneBiologyCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchCOVID-19 Impact on Reproduction