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Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction

Nicola Alessandro De Simone, Matúš Chvojka, Jana Lapešová, Luis Martínez‐Crespo, Petr Slávik, Jan Sokolov, Stephen J. Butler, Hennie Valkenier, Vladimír Šindelář

2022The Journal of Organic Chemistry17 citationsDOIOpen Access PDF

Abstract

Bambusurils are macrocyclic molecules that are known for their high binding affinity and selectivity toward anions. Here, we present the preparation of two bambusurils bearing fluorinated substituents and one carboxylic function. These monofunctionalized bambusurils were conjugated with crown ether and cholesterol units. The resulting conjugates were successfully tested in liquid-liquid extraction of inorganic salts and chloride/bicarbonate transport across lipid bilayers.

Topics & Concepts

ChemistryConjugated systemEtherCrown etherExtraction (chemistry)SelectivityConjugateChlorideBicarbonateMoleculePolymer chemistryCombinatorial chemistryOrganic chemistryIonPolymerMathematical analysisMathematicsCatalysisSupramolecular Self-Assembly in MaterialsMolecular Sensors and Ion DetectionSupramolecular Chemistry and Complexes
Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction | Litcius