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Modification of a nitrocellulose membrane with nanofibers for sensitivity enhancement in lateral flow test strips

Xue Wang, Chao‐Hua Xue, Dong Yang, Shun-Tian Jia, Yaru Ding, Lei Lei, Keyi Gao, Tongtong Jia

2021RSC Advances26 citationsDOIOpen Access PDF

Abstract

We constructed a new type of ICT strip by replacing the conventional nitrocellulose membrane with an electrospin-coated nitrocellulose (ENC) fibrous membrane, and the ICT strip could obtain an HCG detection limit of 0.22 mIU mL<sup>−1</sup>, and an LH detection limit of 0.36 mIU mL<sup>−1</sup>.

Topics & Concepts

NitrocelluloseDetection limitMembraneSTRIPSMaterials scienceSensitivity (control systems)ChemistryNanotechnologyAnalytical Chemistry (journal)ChromatographyComposite materialEngineeringBiochemistryElectronic engineeringBiosensors and Analytical DetectionMicrofluidic and Capillary Electrophoresis ApplicationsAdvanced biosensing and bioanalysis techniques
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