Simultaneous Electrochemical Determination of Paracetamol and Allura Red in Pharmaceutical Doses and Food Using a Mo(VI) Oxide‐Carbon Paste Microcomposite
Édgar Nagles, Mario Ceroni, Claudia Villanueva Huerta, John Hurtado
Abstract
Abstract This work presents a new application for MoO 3 combined with carbon paste to prepare a microcomposite electrode (Mo(VI) Ox /CPE) for the simultaneous determination of paracetamol (PCM) and Allure Red (AR) by square‐wave voltammetry (SWV). The anodic peak currents for PCM and AR were 70.0 and 80.0 % high compared with an unmodified carbon paste electrode. The surface areas of Mo(VI) Ox /CPE and CPE were evaluated by cyclic voltammetry. The detection limit were 0.14 and 0.38 μmol/L for PCM and AR respectively. The relative standard deviations (RSDs) were 2.0 % (n=7). Stability, shelf life and possible interferences were also evaluated with very acceptable results.
Topics & Concepts
Detection limitCarbon paste electrodeCyclic voltammetryElectrochemistryElectrodeVoltammetryMaterials scienceCarbon fibersSquare wavePharmaceutical formulationChemistryNuclear chemistryChromatographyComposite materialPhysical chemistryComposite numberPhysicsQuantum mechanicsVoltageElectrochemical Analysis and ApplicationsElectrochemical sensors and biosensorsDye analysis and toxicity