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Metallaphotoredox-catalyzed C–H activation: regio-selective annulation of allenes with benzamide

Tianlei Li, Jishun Li, Zihao Zhu, Yu-Yuan Chen, Xueyao Li, Qingyun Yang, Jie Xia, Wenxuan Zhang, Chao Zhang, Weidong Pan, Song Wu

2021Organic Chemistry Frontiers25 citationsDOI

Abstract

We have developed an efficient annulation of benzamides with allenes using cobalt and photoredox dual catalysis under an oxygen atmosphere. The transformation features an alternative strategy for the regeneration of a cobalt catalyst with the aid of Eosin Y.

Topics & Concepts

AnnulationChemistryBenzamideCatalysisCobaltEosin YOxygenCombinatorial chemistryPhotochemistryMedicinal chemistryOrganic chemistryPhotocatalysisCatalytic C–H Functionalization MethodsSulfur-Based Synthesis TechniquesRadical Photochemical Reactions
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