Palladium-catalyzed ligand-regulated divergent synthesis of pyrrole[2,3-<i>b</i>]indoles and ureas from 2-ethynylanilines and isocyanides
Min Zhang, Yongpeng Zheng, Yangbin Jin, Huanfeng Jiang, Wanqing Wu
Abstract
oxidative amination of anilines with isocyanides in the presence of a ligand were obtained both in moderate to good yields with high selectivity. In this chemistry, cyclic and acyclic products were easily accessed with the same starting materials under the regulation of the ligand.
Topics & Concepts
PyrrolePalladiumLigand (biochemistry)CatalysisTandemChemistryCombinatorial chemistryOrganic chemistryMaterials scienceReceptorBiochemistryComposite materialCatalytic C–H Functionalization MethodsSynthesis and Characterization of PyrrolesCatalytic Cross-Coupling Reactions