New bis(pyrazolo[3,4-b]pyridines) and bis(thieno[2,3-b]pyridines) as potential acetylcholinesterase inhibitors: synthesis, in vitro and SwissADME prediction study
Ahmed A. M. Ahmed, Ahmed E. M. Mekky, Sherif M. H. Sanad
Topics & Concepts
ChemistryPyridineSodium ethoxideAcetylcholinesteraseDPPHSynthonLipophilicityMedicinal chemistryReagentAntioxidantOrganic chemistryStereochemistryEnzymeEthanolSynthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsComputational Drug Discovery Methods