Emergence of Difficult-to-Treat Tinea Corporis Caused by <i>Trichophyton mentagrophytes</i> Complex Isolates, Paris, France
Sarah Dellière, Brune Joannard, Mazouz Benderdouche, Anselme Mingui, Maud Gits‐Muselli, Samia Hamane, Alexandre Alanio, A. Petit, G. Gabison, M. Bagot, Stéphane Bretagne
Abstract
We describe 7 cases of extensive tinea corporis since 2018 in a hospital in Paris, France, after failure to cure with terbinafine. Molecular analysis indicated Trichophyton mentagrophytes internal transcribed spacer type VIII (T. indotineae). This strain, which has mutations in the squalene epoxidase gene, is spreading on the Indian subcontinent.
Topics & Concepts
TerbinafineTinea capitisTrichophytonInternal transcribed spacerSqualene monooxygenaseDermatophyteDermatologyMedicineMicrobiologyBiologyGeneGeneticsRibosomal RNAAntifungalItraconazoleBiosynthesisNail Diseases and TreatmentsFungal Infections and StudiesOral Health Pathology and Treatment