Usefulness of cell-penetrating peptides and penetration accelerating sequence for nose-to-brain delivery of glucagon-like peptide-2
Tomomi Akita, Ryosuke Kimura, Saki Akaguma, Mio Nagai, Yusuke Nakao, Mamiko Tsugane, Hiroaki Suzuki, Jun-Ichiro Oka, Chikamasa Yamashita
Topics & Concepts
Paracellular transportNasal administrationTranscellularPharmacologyIn vivoDrug deliverySystemic administrationCell-penetrating peptideIntestinal epitheliumChemistryMedicinePeptideBiologyPathologyEpitheliumBiochemistryPermeability (electromagnetism)BiotechnologyMembraneOrganic chemistryRNA Interference and Gene DeliveryLipid Membrane Structure and BehaviorAdvanced Drug Delivery Systems