Etoposide in combination with erastin synergistically altered iron homeostasis and induced ferroptotic cell death through regulating IREB2/FPN1 expression in estrogen receptor positive-breast cancer cells
Erva Özkan, Filiz Bakar‐Ates
Topics & Concepts
Programmed cell deathGPX4Oxidative stressEtoposideLipid peroxidationApoptosisViability assayCancer cellPharmacologyChemistryCancer researchEstrogen receptorIntracellularGlutathioneGlutathione peroxidaseCancerBreast cancerMedicineBiochemistryInternal medicineCatalaseChemotherapyEnzymeFerroptosis and cancer prognosisCancer, Lipids, and MetabolismClusterin in disease pathology