Litcius/Paper detail

Xanthohumol Alleviates T2DM-induced Liver Steatosis and Fibrosis by Mediating the NRF2/RAGE/NF-κB Signaling Pathway

Wei Wang, Zhixi Chen, Tiansheng Zheng, Ming Zhang

2021Future Medicinal Chemistry33 citationsDOI

Abstract

XH protected against T2DM-induced liver steatosis and fibrosis by mediating NRF2/AGE/RAGE/NF-κB signaling.

Topics & Concepts

SteatosisRage (emotion)GlycationXanthohumolWestern blotFibrosisFatty liverNonalcoholic fatty liver diseaseGene knockdownMedicineInternal medicineEndocrinologyReceptorChemistryBiologyApoptosisBiochemistryDiseaseGeneKey (lock)EcologyNeuroscienceHops Chemistry and ApplicationsLipid metabolism and biosynthesisGenomics, phytochemicals, and oxidative stress