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dCas9-VPR-mediated transcriptional activation of functionally equivalent genes for gene therapy

Lisa Maria Riedmayr, Klara Sonnie Hinrichsmeyer, Nina Karguth, Sybille Böhm, Victoria Splith, Stylianos Michalakis, Elvir Bećirović

2022Nature Protocols28 citationsDOI

Topics & Concepts

GeneBiologyComputational biologyGeneticsGenetic enhancementRegulation of gene expressionFunction (biology)MutationCRISPR and Genetic EngineeringVirus-based gene therapy researchRetinal Development and Disorders
dCas9-VPR-mediated transcriptional activation of functionally equivalent genes for gene therapy | Litcius