Chlorpyrifos induces neuronal cell death via both oxidative stress and Akt activation downstream-regulated CHOP-triggered apoptotic pathways
Jhe-Wei Lin, Shih-Chang Fu, Jui‐Ming Liu, Shing‐Hwa Liu, Kuan-I Lee, Kai‐Min Fang, Ren‐Jun Hsu, Chun-Fa Huang, Kun-Min Liu, Kai‐Chih Chang, Chin‐Chuan Su, Ya‐Wen Chen
Topics & Concepts
Protein kinase BApoptosisPI3K/AKT/mTOR pathwayProgrammed cell deathCell biologyOxidative stressNeurotoxicityChemistryReactive oxygen speciesBiologyPhosphorylationViability assayCancer researchSignal transductionBiochemistryToxicityOrganic chemistryPesticide Exposure and ToxicityHeavy Metal Exposure and ToxicityCarcinogens and Genotoxicity Assessment