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Targeting SIK3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of HDAC4 in a mouse model of Alzheimer’s disease

Xiaoman Dai, Anlan Lin, Lv-Ping Zhuang, Qingyong Zeng, Lili Cai, Yuanxiang Wei, Hongjie Liang, Weijie Gao, Jing Zhang, Xiaochun Chen

2023Neuropsychopharmacology16 citationsDOIOpen Access PDF

Topics & Concepts

Synaptic plasticityNeuroscienceLong-term potentiationBiologyCell biologyDendritic spineHippocampal formationGeneticsReceptorHistone Deacetylase Inhibitors ResearchGenetics and Neurodevelopmental DisordersNeurogenesis and neuroplasticity mechanisms
Targeting SIK3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of HDAC4 in a mouse model of Alzheimer’s disease | Litcius