Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans
Steven R. H. Beach, Mei Ling Ong, Man‐Kit Lei, Sierra Carter, Ronald L. Simons, Frederick X. Gibbons, Robert A. Philibert
Abstract
methylation may help explain intrinsic accelerated ageing and elevated cardiometabolic risk in adulthood for Black Americans.
Topics & Concepts
MethylationDNA methylationAgeingBody mass indexFKBP5CpG siteBiologyYoung adultGerontologyMedicineDemographyOncologyPhysiologyGeneticsEndocrinologyGene expressionGeneSociologyGlucocorticoid receptorBirth, Development, and HealthEpigenetics and DNA MethylationAdolescent and Pediatric Healthcare