Litcius/Paper detail

Solitary neurofibroma over lower lip: A rare manifestation

B Spoorthy, ShishiraR Jartarkar, Sruthi Kareddy

2022Journal of Cutaneous and Aesthetic Surgery10 citationsDOIOpen Access PDF

Abstract

Neurofibromas are common nerve sheath tumors, occurring either sporadically or associated with Von Recklinghausen's disease. Only 6.5% of solitary lesions are seen to involve the oral cavity without any features of neurofibromatosis type 1 (NF-1). It presents as a soft, skin-colored nodule with a characteristic buttonhole invagination. Histologically, it is an unencapsulated lesion consisting of proliferated neural elements, with a background of mucin and mast cells. Surgical excision is the treatment of choice. A 49-year-old female patient presented with a 35-year history of single, asymptomatic lesion over the lower lip, with no features of NF-1. On the basis of the history, histopathological findings, and dermoscopy, a diagnosis of neurofibroma was made and the lesion was excised, with no recurrence over a period of 1 year. The present case report has been reported for its interesting presentation and unusual site of involvement.

Topics & Concepts

MedicineLesionNeurofibromaNeurofibromatosisAsymptomaticPathologyNodule (geology)Presentation (obstetrics)DermatologyRadiologyBiologyPaleontologyNeurofibromatosis and Schwannoma CasesSoft tissue tumor case studiesSoft tissue tumors and treatment