Late-stage diversification strategy for synthesizing ynamides through copper-catalyzed diynylation and azide–alkyne cycloaddition
Ryohei Kawakami, Suguru Usui, Norihiro Tada, Akichika Itoh
Abstract
A late-stage diversification strategy for synthesizing ynamides has been developed.
Topics & Concepts
CycloadditionAlkyneChemistryAzideCatalysisCombinatorial chemistryNucleosideCopperElectrophileOrganic chemistryStereochemistryCatalytic Alkyne ReactionsClick Chemistry and ApplicationsSulfur-Based Synthesis Techniques