Mapping the rat gastric slow-wave conduction pathway: bridging in vitro and in vivo methods, revealing a loosely coupled region in the distal stomach
Omkar N. Athavale, Madeleine R. Di Natale, Recep Avci, Alys R. Clark, John B. Furness, Leo K. Cheng, Peng Du
2024American Journal of Physiology-Gastrointestinal and Liver Physiology14 citationsDOIOpen Access PDF
Abstract
Mapping of rat gastric slow waves showed regional variations in their organization. In some subjects, separate wavefronts propagated near the lesser and greater curvatures with a loosely coupled region near the midline, between the wavefronts, having a varying slow-wave origin. Furthermore, simultaneous intracellular and extracellular recordings were concordant and independent of movement artifacts, indicating that extracellular recordings can be interpreted in terms of their intracellular counterparts when intracellular recording is not possible.
Topics & Concepts
Curvatures of the stomachExtracellularAntrumInterstitial cell of CajalMotilityCurvatureIn vivoGastric antrumAmplitudeWavefrontPyloric AntrumChemistryPhysicsBiophysicsAnatomyStomachBiologyOpticsGeometryEndocrinologyMathematicsCell biologySmooth muscleBiochemistryBiotechnologyGastrointestinal motility and disordersGastroesophageal reflux and treatmentsHelicobacter pylori-related gastroenterology studies