Detection of Structural Rearrangements in Embryos
Svetlana Madjunkova, Yogi Sundaravadanam, Ran Antes, Rina Abramov, Siwei Chen, Yin Yin, Philip C. Zuzarte, Sergey I. Moskovtsev, Lars Jorgensen, Ari Baratz, Jared T. Simpson, Clifford Librach
Abstract
Balanced Translocations in Embryos Balanced chromosomal rearrangements are associated with infertility and recurrent miscarriage but are difficult to detect. In this study, long-read DNA sequencing...
Topics & Concepts
MedicineEmbryoComputational biologyGeneticsBiologyPrenatal Screening and DiagnosticsGenomic variations and chromosomal abnormalitiesChromosomal and Genetic Variations