De novo construction of T cell compartment in humanized mice engrafted with iPSC-derived thymus organoids
Ann E. Zeleniak, Connor Wiegand, Wen Liu, Catherine McCormick, K. Ravikumar, Amir Alavi, Haonan Guan, Suzanne Bertera, Robert Lakomy, Asako Tajima, Henry Cohen, Stephanie M. Wong, Lamé Balikani, Benjamin Mizerak, Ziv Bar‐Joseph, Massimo Trucco, Ipsita Banerjee, Yong Fan
Topics & Concepts
BiologyInduced pluripotent stem cellHumanized mouseImmune systemOrganoidT cellImmunologyCell biologyPopulationHaematopoiesisCompartment (ship)Stem cellCancer researchEmbryonic stem cellMedicineGeneticsOceanographyGeneGeologyEnvironmental healthCAR-T cell therapy researchPluripotent Stem Cells ResearchCRISPR and Genetic Engineering