Liquid-Liquid Phase Separation of Tau Driven by Hydrophobic Interaction Facilitates Fibrillization of Tau
Yanxian Lin, Yann Fichou, Andrew P. Longhini, Luana C. Llanes, Pengyi Yin, Guillermo C. Bazan, Kenneth S. Kosik, Songi Han
Topics & Concepts
CoacervateChemistryFibrilIntrinsically disordered proteinsProtein aggregationTau proteinBiophysicsBiochemistryBiologyAlzheimer's diseasePathologyDiseaseMedicineRNA Research and SplicingAdvanced Mathematical Modeling in EngineeringStochastic processes and statistical mechanics