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STING up-regulates VEGF expression in oxidative stress-induced senescence of retinal pigment epithelium via NF-κB/HIF-1α pathway

Qingqiu Chen, Li Tang, Yi Zhang, Chengyu Wan, Xiuxian Yu, Yuman Dong, Xiaoting Chen, Xueling Wang, Ning Li, Guang Xin, Meixia Zhang, Zhen Chen, Hai Niu, Wen Huang

2022Life Sciences52 citationsDOI

Topics & Concepts

Oxidative stressRetinal pigment epitheliumSenescenceVascular endothelial growth factorCell biologyAngiogenesisMacular degenerationDNA damageSignal transductionBiologyRetinalCancer researchMedicineEndocrinologyVEGF receptorsOphthalmologyBiochemistryDNAinterferon and immune responsesOcular Diseases and Behçet’s SyndromeRetinal Diseases and Treatments
STING up-regulates VEGF expression in oxidative stress-induced senescence of retinal pigment epithelium via NF-κB/HIF-1α pathway | Litcius