A dual-fluorophore sensor approach for ratiometric fluorescence imaging of potassium in living cells
Zeming Wang, Tyler C. Detomasi, Christopher J. Chang
Abstract
normal breast cells. This work provides a unique chemical tool for the study of intracellular potassium dynamics and a starting point for the design of other ratiometric fluorescent sensors based on two-fluorophore approaches that do not rely on FRET or related energy transfer designs.
Topics & Concepts
IntracellularFluorophorePotassiumFluorescenceBiophysicsChemistryCellContraction (grammar)Cell biologyBiochemistryBiologyEndocrinologyOpticsPhysicsOrganic chemistryMolecular Sensors and Ion DetectionAnalytical Chemistry and SensorsElectrochemical sensors and biosensors