RSK2 inactivation cooperates with AXIN1 inactivation or β-catenin activation to promote hepatocarcinogenesis
Samantha Schaeffer, Barkha Gupta, Anna-Line Calatayud, Julien Caldéraro, Stefano Caruso, Théo Z. Hirsch, Laura Pelletier, Jessica Zucman‐Rossi, Sandra Rebouissou
Topics & Concepts
HCCSCancer researchBiologyMAPK/ERK pathwayMutationHepatocellular carcinomaTransgeneTranscriptomeLiver cancerSuppressorKinaseGeneCell biologyGeneticsGene expressionMelanoma and MAPK PathwaysProtein Kinase Regulation and GTPase SignalingCytokine Signaling Pathways and Interactions