Outer Membrane Vesicles of Gram-Negative Bacteria: An Outlook on Biogenesis
Eric Daniel Ávila-Calderón, María del Socorro Ruiz-Palma, Ma. Guadalupe Aguilera‐Arreola, Norma Velázquez‐Guadarrama, Enrico A. Ruíz, Zulema Gómez-Lunar, Sharon G. Witonsky, Araceli Contreras-Rodríguez
Abstract
Outer membrane vesicles (OMVs) from Gram-negative bacteria were first described more than 50 years ago. However, the molecular mechanisms involved in biogenesis began to be studied only in the last few decades. Presently, the biogenesis and molecular mechanisms for their release are not completely known. This review covers the most recent information on cellular components involved in OMV biogenesis, such as lipoproteins and outer membrane proteins, lipopolysaccharide, phospholipids, quorum-sensing molecules, and flagella.
Topics & Concepts
BiogenesisBacterial outer membraneVesicleBacteriaFlagellumBiologyCell biologyGram-negative bacteriaLipopolysaccharideQuorum sensingMembraneChemistryMicrobiologyBiochemistryBiofilmEscherichia coliGeneticsGeneEndocrinologyBacterial Infections and VaccinesLegionella and Acanthamoeba researchPneumonia and Respiratory Infections