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Study of dispersion of drug in blood flow with the impact of chemical reaction through stenosed artery

Sapna Ratan, A Ali N Zaman, M Sajid, J Nieto, A Torres, B Bazrov, D Biswas, R Laskar, S Chakravarty, A Datta, S Chakravarty, A Datta, S Chakravarty, J Damiano, T Bardin, R Dash, G Jayaraman, K Mehta, G Deheri, R Patel, T Patel, S Echarm, G Kurland, R Ellahi, S Rahman, M Mudassar, Nadeem Vafai, K, J Forrester, D Young, D Fry, W Gill, R Sankarasubramanian, N Jaafar, Y Yatim, D Sankar, N Jaafar, Y Yatim, D Sankar, D Ku, R Kudenatti, N Murulidhara, H Patil, J Kumar, R Raghavendra, R Kumar, S Shah, V Kumar, S Shah, P Kumar, S Shah, J Lee, Y Fung, Mak Miah, S Hossain, S Salehin, J Misra, G Shit, J Misra, G Shit, N Naduvinamani, S Fathima, P Hiremath, N Naduvinamani, G Savitramma, T Petrila, D Tarif, P Pustovsk, J Hron, J Mlek, K Rajagopal, J Rana, Pvsn Murthy, N Ratchagar, K Vijaya, J Rana, Pvsn Murthy, M Sadique, S Shah, S Shah, G Thurston, D Young, F Tsai

2022International Journal of Biosciences (IJB)31 citationsDOIOpen Access PDF

Abstract

The present study mathematically examines the dispersion of drugs in blood flow through cosine and sineshaped stenosed arteries with the impact of chemical reaction where blood has been considered as Herschel-Bulkley blood fluid model. The deposition of cholesterols, fats and lipids plaques on the artery wall causes stenosis and leads to the narrowing of the artery. The stenosis shape and chemical reaction have an imperative impact on the effectiveness of the drug dispersion. The nonlinear differential equations are solved to achieve blood velocity. The dispersion function is gained in this model to generalized dispersion expression. Results

Topics & Concepts

Blood flowDrugDispersion (optics)ArteryChemistryBiomedical engineeringMedicineMaterials sciencePharmacologyChemical engineeringCardiologyEngineeringPhysicsOpticsPolymer Science and ApplicationsAdsorption, diffusion, and thermodynamic properties of materials
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