Nrf2 inhibition sensitizes breast cancer stem cells to ionizing radiation via suppressing DNA repair
Shenghui Qin, Xiaoyuan He, Houmin Lin, Bradley A. Schulte, Mingfeng Zhao, Kenneth D. Tew, Gavin Y. Wang
Topics & Concepts
RadioresistanceGene knockdownCancer researchSulforaphaneCancer stem cellDNA damageChemistryCancer cellTriple-negative breast cancerCancerDNA repairStem cellApoptosisBiologyBreast cancerCell biologyCell cultureDNABiochemistryGeneticsGenomics, phytochemicals, and oxidative stressGlutathione Transferases and PolymorphismsEffects of Radiation Exposure