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Design, synthesis and evaluation of cinnamic acid hybrids as multi-target-directed agents for the treatment of Alzheimer’s disease

Keren Wang, Jian Shi, Yi Zhou, Ying He, Jing Mi, Jing Yang, Shuang Liu, Xiangcheng Tang, Wenmin Liu, Zhenghuai Tan, Zhipei Sang

2021Bioorganic Chemistry31 citationsDOI

Topics & Concepts

ChemistryIn vivoLead compoundIC50Cinnamic acidPharmacologyAntioxidantNeuroprotectionBiochemistryStereochemistryIn vitroCombinatorial chemistryBiotechnologyMedicineBiologyCholinesterase and Neurodegenerative DiseasesMedicinal Plants and NeuroprotectionAlzheimer's disease research and treatments
Design, synthesis and evaluation of cinnamic acid hybrids as multi-target-directed agents for the treatment of Alzheimer’s disease | Litcius