Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000–2016: a Danish population‐based study
Lasse Hjort Jakobsen, Anne Stidsholt Roug, Andreas Kiesbye Øvlisen, Claus Werenberg Marcher, Hans Beier Ommen, Kim Theilgaard‐Mönch, Peter Möller, Claudia Schöllkopf, Daniel Tuyet Kristensen, Therese Maria Henriette Naur, Martin Bøgsted, Tarec Christoffer El‐Galaly, Marianne Tang Severinsen
Abstract
In the present study, we quantify the progress in overall survival (OS) during the period 2000-2016 among Danish patients with acute myeloid leukaemia (AML). This population-based study, including 3820 adult patients with AML, demonstrates a significantly improved OS over time with the 2-year age-standardised OS increasing from 22% in 2002 to 31% in 2016. The improvement in OS was exclusively seen in patients with AML aged ≥50 years, with absolute improvements in 2-year OS from 2002 to 2016 of ≥10% among patients aged 50-75 years and a small absolute increase in those aged >75 years.