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Species-Specific Analysis of Bacterial Vaginosis-Associated Bacteria

John Osei Sekyere, Ayodeji B. Oyenihi, Jason Trama, Martin E. Adelson

2023Microbiology Spectrum13 citationsDOIOpen Access PDF

Abstract

For many years since 2005, BVAB, an important pathogen of the female vaginal tract that is associated with BV, has been identified using PCR without knowing its actual species. Without a full genome of these pathogens, a better understanding of their pathogenicity, treatment, resistance, and diagnostics cannot be reached. In this analysis, we use the DNA of BVAB-1, -2, and -3 to determine their actual species to enhance further research into their pathogenicity, resistance, diagnosis, and treatment.

Topics & Concepts

Bacterial vaginosisPathogenBiologyPathogenicityMicrobiologyPathogenicity islandBacteriaGenomeGeneticsGeneReproductive tract infections researchGut microbiota and healthBacterial Identification and Susceptibility Testing