Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27
Thanigaimalai Pillaiyar, Francesca Rosato, Monika Woźniak, Jérémy Blavier, Maëlle Charles, Céline Laschet, Thales Kronenberger, Christa E. Müller, Julien Hanson
Topics & Concepts
BenzamideChemistryAgonistReceptorPartial agonistStereochemistryIntrinsic activityG protein-coupled receptorStructure–activity relationshipBiological activityG proteinAntagonistPharmacologyBiochemistryIn vitroBiologyReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyPharmacogenetics and Drug Metabolism