Effects of a Plant-Based High-Protein Diet on Fatigue in Breast Cancer Patients Undergoing Adjuvant Chemotherapy – a Randomized Controlled Trial
Esther Sathiaraj, Kamar Afshan, R Sruthi, Arti Jadoni, Karthik Murugan, Shekhar Patil, Radheshyam Naik
Abstract
BACKGROUND: Breast cancer patients undergoing chemotherapy (CT) experience fatigue and other side-effects. Studies exploring interventions with a plant-based, high-protein diet on fatigue and body composition are lacking. The effects of these interventions on fatigue, body mass index (BMI), and body composition were evaluated. METHOD: = 103) were randomly assigned to the intervention or control group. Study outcomes included fatigue using fatigue symptom inventory and body composition using bioelectric impedance analyzer done at the start of CT, 3rd CT, and 3 weeks after CT. Linear mixed models were used to compare groups over time. RESULTS: < 0.05). CONCLUSIONS: A plant-based, high-protein diet during CT resulted in positive changes in fatigue, BMI and body composition.