Polycaprolactone and its derivatives for drug delivery
Ranjitsinh Pawar, Anam Pathan, Srishti Nagaraj, Harshad S. Kapare, Prabhanjan Giram, Ravindra Wavhale
Abstract
Abstract Polycaprolactone (PCL) is polymer of 21st centuries. PCL is a biodegradable and biocompatible polymer used for various healthcare applications. This review explores the properties, synthesis, and processing of PCL. The use of PCL polymer for nanoparticles (NPs), microparticles, films, and fibers offers several advantages for biomedical applications. The review highlights the potential of PCL‐based materials for tissue engineering, drug delivery, wound healing, and implantable medical devices. We also critically analyzed challenges in PCL‐based materials and the strategies used to overcome for successful translation into clinical applications. Overall, this review provides a comprehensive overview of PCL as a valuable biomaterial for healthcare applications.