Neutrophil-mediated delivery of the combination of colistin and azithromycin for the treatment of bacterial infection
Jiacong Gao, Xueyan Hu, Congjuan Xu, Mingming Guo, Shouyi Li, Fan Yang, Xiaolei Pan, Fangyu Zhou, Yongxin Jin, Fang Bai, Zhihui Cheng, Zhenhua Wu, Shuiping Chen, Xinglu Huang, Weihui Wu
Abstract
infection in an acute pneumonia model. This study provides a potential effective therapeutic approach for the treatment of bacterial infections.
Topics & Concepts
ColistinAzithromycinAntibioticsPseudomonas aeruginosaPneumoniaNeutrophil extracellular trapsMicrobiologyDrugMedicinePharmacologyImmunologyBiologyBacteriaInflammationInternal medicineGeneticsAntibiotic Resistance in BacteriaImmune Response and InflammationAntimicrobial Peptides and Activities