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Engineering CAR-T cells to activate small-molecule drugs in situ

Thomas J. Gardner, J. Peter Lee, Christopher M. Bourne, Dinali Wijewarnasuriya, Nihar Kinarivala, Keifer G. Kurtz, Broderick C. Corless, Megan M. Dacek, Aaron Y. Chang, George Mo, Kha M. Nguyen, Renier J. Brentjens, Derek S. Tan, David A. Scheinberg

2021Nature Chemical Biology77 citationsDOIOpen Access PDF

Topics & Concepts

In situSmall moleculeChemistryMoleculeComputational biologyCell biologyBiologyBiochemistryOrganic chemistryCAR-T cell therapy researchNanowire Synthesis and Applications
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