The reductive half-reaction of two bifurcating electron-transferring flavoproteins
Wayne Vigil, Jessica Tran, Dimitri Niks, Gerrit J. Schut, Xiaoxuan Ge, Michael W. W. Adams, Russ Hille
Abstract
, with reduction of the now fully reoxidized bifurcating FAD by a second equivalent of NADH. We suggest that the crossing and uncrossing of the reduction half-potentials of the bifurcating FAD is due to specific conformational changes that have been structurally characterized.
Topics & Concepts
FlavoproteinFerredoxinSemiquinoneOxidoreductaseFlavin adenine dinucleotideFlavin groupChemistryElectron transport chainSodium dithioniteFlavodoxinDithioniteNAD+ kinasePhotochemistryMoietyCofactorStereochemistryBiochemistryEnzymeQuinoneInorganic chemistryPhotosynthetic Processes and MechanismsPorphyrin Metabolism and DisordersMetal-Catalyzed Oxygenation Mechanisms