Manumycin polyketides act as molecular glues between UBR7 and P53
Yosuke Isobe, Mikiko Okumura, Lynn M. McGregor, Scott M. Brittain, Michael D. Jones, Xiaoyou Liang, R. Larry White, William C. Forrester, Jeffrey M. McKenna, John A. Tallarico, Markus Schirle, Thomas J. Maimone, Daniel K. Nomura
Topics & Concepts
Ubiquitin ligaseNatural productSmall moleculeBiologyDNA ligaseComputational biologySuppressorCell biologyUbiquitinChemistryBiochemistryGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis