Litcius/Paper detail

Ultra-rapid real-time microfluidic RT-PCR instrument for nucleic acid analysis

Renna L. Nouwairi, Larissa L. Cunha, Rachelle Turiello, Orion N. Scott, Jeff Hickey, Scott Thomson, Stuart Knowles, Jeff D. Chapman, James P. Landers

2022Lab on a Chip36 citationsDOIOpen Access PDF

Abstract

, respectively. Judicious selection and strategic placement of the thermal cyclers and fluorescence detector relative to the microchip enable synchronized thermal cycling and fluorescence monitoring, further reducing time-to-result. Robust amplification and detection of DNA and RNA targets empowers laboratories to achieve rapid, actionable information in endless applications.

Topics & Concepts

Nucleic acidMicrofluidicsReal-time polymerase chain reactionNucleic acid detectionPolymerase chain reactionTemperature cyclingNucleic acid quantitationComputer scienceNanotechnologyComputational biologyChemistryMaterials scienceBiologyThermalPhysicsBiochemistryMeteorologyGeneMicrofluidic and Capillary Electrophoresis ApplicationsBiosensors and Analytical DetectionInnovative Microfluidic and Catalytic Techniques Innovation