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Molecular grammars of predicted intrinsically disordered regions that span the human proteome

Kiersten M. Ruff, Matthew R. King, Alexander W. Ying, Vicky Liu, Avnika Pant, Whitney E Lieberman, Min Kyung Shinn, Xiaolei Su, Cigall Kadoch, Rohit V. Pappu

2025Cell27 citationsDOIOpen Access PDF

Topics & Concepts

BiologyComputational biologyExtant taxonProteomeHuman proteome projectRule-based machine translationEvolutionary biologyAmino acidIntrinsically disordered proteinsMolecular evolutionTranslation (biology)Peptide sequenceAmino acid residueSortingGeneticsProtein structurePosttranslational modificationSequence (biology)ProteomicsBiochemistryBiological systemGenomics and Rare DiseasesRNA and protein synthesis mechanismsGenomics and Phylogenetic Studies
Molecular grammars of predicted intrinsically disordered regions that span the human proteome | Litcius