TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading
Yin Xu, Shuqi Du, Jacob Marsh, Kanta Horie, Chihiro Sato, Andrea Ballabio, Celeste M. Karch, David M. Holtzman, Hui Zheng
Topics & Concepts
TFEBTauopathyCell biologyExocytosisTau proteinExtracellularChemistrySecretionAutophagyNeuroscienceBiologyAlzheimer's diseaseNeurodegenerationBiochemistryInternal medicineApoptosisDiseaseMedicineAlzheimer's disease research and treatmentsCellular transport and secretionNeuroscience and Neuropharmacology Research