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Wet spinning of sodium carboxymethyl cellulose–sodium caseinate hydrogel fibres: relationship between rheology and spinnability

Lathika Vaniyan, Pallab Kumar Borah, Galina E. Pavlovskaya, Nicholas J. Terrill, Joshua E. S. J. Reid, Michael W. Boehm, Philippe Prochasson, Reed A. Nicholson, Stefan K. Baier, Gleb E. Yakubov

2025Soft Matter8 citationsDOIOpen Access PDF

Abstract

Mimicking the fibrous structures of meat is a significant challenge as natural plant protein assemblies lack the fibrous organisation ubiquitous in mammalian muscle tissues. In this work, wet-spun hydrogel fibres resembling the anisotropic fibrous microstructure of meat are fabricated using carboxymethyl cellulose as a model polysaccharide and sodium caseinate as a model protein which are crosslinked using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC). Hydrogels and spun fibres were characterised using a combination of rheology (shear, oscillatory, and extensional), microscopy (light, polarised, and fluorescence), rheo-NMR, and X-ray diffraction. Examination of structuring behaviour under shear uncovered a relationship between enhanced biopolymer orientation along the fibre axis and a viscoelastic time-dependent ageing window for optimal hydrogel spinnability. This study provides novel rheological and structural insights into mechanisms of protein-polysaccharide assembly that may prove instrumental for development of tuneable fibres for applications in plant-based foods, tissue engineering, and biomaterials.

Topics & Concepts

Carboxymethyl celluloseSpinningRheologyChemical engineeringSodium alginateCelluloseSodiumMaterials sciencePolymer scienceGelatinSodium CaseinateChemistryPolymer chemistryComposite materialOrganic chemistryChromatographyEngineeringTextile materials and evaluationsPolysaccharides Composition and Applications
Wet spinning of sodium carboxymethyl cellulose–sodium caseinate hydrogel fibres: relationship between rheology and spinnability | Litcius