Multivalent pyrrolidines acting as pharmacological chaperones against Gaucher disease
Marc Borie-Guichot, My Lan Tran, Virginie Garcia, Abdelouahd Oukhrib, Frédéric Rodriguez, Cédric‐Olivier Turrin, Thierry Levade, Yves Génisson, Stéphanie Ballereau, Cécile Baudoin‐Dehoux
Topics & Concepts
IminosugarChemistryGlucocerebrosidaseEnantiomerDocking (animal)AzideCombinatorial chemistryCycloadditionBiochemistryStereochemistryEnzymeOrganic chemistryCatalysisNursingMedicineLysosomal Storage Disorders ResearchCarbohydrate Chemistry and SynthesisGlycosylation and Glycoproteins Research