A DNAzyme-augmented bioorthogonal catalysis system for synergistic cancer therapy
Yawen You, Hao Liu, Jiawei Zhu, Yibo Wang, Fang Pu, Jinsong Ren, Xiaogang Qu
Abstract
drug synthesis and chemodynamic therapy exhibited excellent anti-cancer effects and minimal side effects. The study offers a simple and novel avenue to develop highly efficient and safe bioorthogonal catalysts for biological applications.
Topics & Concepts
Bioorthogonal chemistryDeoxyribozymeCombinatorial chemistryChemistryCatalysisProdrugClick chemistryCancer therapyNanotechnologyCancerBiochemistryDNAMaterials scienceBiologyGeneticsClick Chemistry and ApplicationsAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery