Executive Summary: Clinical Practice Guideline for Autosomal Dominant Polycystic Kidney Disease in China
Changlin Mei, Cheng Xue, Shengqiang Yu, Bing Dai, Jianghua Chen, Ying Li, Li-Meng Chen, Zhangsuo Liu, Yonggui Wu, Zhao Hu, Yan Zha, Hong Liu, Yong-Ze Zhuang, Chun Zhang, Xiangcheng Xiao, Yue Wang, Guisen Li, Yiyi Ma, Lin Li
Abstract
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease, with a prevalence of 1/2,500-1/1,000, and it affects 1.25 million people in China. ADPKD is responsible for nearly 5% of end-stage renal disease cases, which leads to a major burden on public health. In 2016, the Chinese working group developed guidelines for the diagnosis and treatment of ADPKD, which promoted the clinical management of ADPKD in China. In the last 3 years, Chinese clinicians have deepened their understanding and standardized the management of ADPKD, and several basic and clinical studies on ADPKD have been conducted. In combination with international guidelines and research results, the working group updated the ADPKD guidelines in China. This guideline includes 5 chapters: introduction, diagnosis, kidney disease progression monitoring, treatment, and family planning. We highlight the main recommendations and suggestions of the ADPKD guidelines in this summary.