Design, synthesis, and molecular docking study of some 2-((7-chloroquinolin-4-yl) amino) benzohydrazide Schiff bases as potential Eg5 inhibitory agents
Rohini S. Kavalapure, Shankar G. Alegaon, U. Venkatasubramanian, A. Soundarya Priya, Shriram D. Ranade, Pukar Khanal, Sanjay Mishra, Dhanashree Patil, Preeti Salve, Sunil Jalalpure
Topics & Concepts
ChemistrySchiff baseDocking (animal)IC50Inhibitory postsynaptic potentialActive siteStereochemistryProton NMRCarbon-13 NMRCombinatorial chemistryAmino acidIn vitroEnzymeBiochemistryNursingBiologyNeuroscienceMedicineCancer Mechanisms and TherapyMicrotubule and mitosis dynamicsSynthesis and biological activity